From owner-structural-nmr@net.bio.net Wed Feb 04 22:00:00 1998 Path: biosci!biosci!not-for-mail From: facelli@shielding.chpc.utah.edu (Julio Facelli) Newsgroups: bionet.structural-nmr Subject: Modeling Chemical Shifts Date: 5 Feb 1998 12:07:55 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 52 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <199802051957.MAA18135@shielding.chpc.utah.edu> NNTP-Posting-Host: net.bio.net Dear NMR Spectroscopist: You may be interest in this ACS Symposium on Modeling Chemical Shifts. We are sending this e-mail to update you on the development of the conference. We have established a web site for the conference (http://www.chpc.utah.edu/~usijcf/boston.html). In this site you will find all the logistical information regarding registration, accommodations, official ACS abstract forms, instructions for the authors, etc. We will continue to update the site as more information becomes available. The publication office of the ACS has agreed to publish the proceedings of the symposium, authors' kits will be distributed early in June. In addition, we have asked the PHYS division of ACS to co-sponsor this symposium. Angel and myself will provide an overview chapter for the proceedings, if you have any suggestions please let us know. Finally, let me remind you of some of the important deadlines for the conference: -Abstracts (in official ACS form) due April 15, 1998. -Authors' kits will be distributed June 1, 1998. -Registration and Housing begins June 22, 1998. -Draft manuscripts (14 pages max.) for the proceedings due at the conference, August 23-27, 1998. -Final manuscripts, camera ready, due December 31, 1998. ACS plans to have the book out in June, 1999, up to three complimentary copies will be given to the authors of the chapters. Once again thank for your interest in the conference, looking forward to see you at Boston. Julio Facelli Angel de Dios ________________________________________________________________________________ DR JULIO C FACELLI DIRECTOR UNIVERSITY OF UTAH CENTER FOR HIGH PERFORMANCE COMPUTING 155 S 1452 E RM 405 SALT LAKE CITY UT 84112-0190 Phone (801)-581-7529 Fax (801)-585-5366 e-mail facelli@chpc.utah.edu ________________________________________________________________________________ From owner-structural-nmr@net.bio.net Wed Feb 04 22:00:00 1998 Path: biosci!biosci!not-for-mail From: Isabella Felli Newsgroups: bionet.structural-nmr Subject: Doc and Post-Doc positions in Florence!!!! Date: 5 Feb 1998 10:30:18 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 56 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <6bbtn6$4ln@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net A doctoral and a post-doctoral position are available at the University of Florence to study the structure and dynamics of paramagnetic metalloproteins. The NMR laboratory of Florence is a Large Scale Facility of the European Union and is equipped with: 800 MHz 600 MHz 500 MHz 200 MHz 90 MHz 4-60 MHz non-commercial field cylcing relaxometer prototype of a fast field cycling relaxometer A powerful parallel SP2 IBM computer and several workstations provide outstanding computer capabilities and allow to process NMR data, calculate protein and DNA structures and run molecular dynamics simulations. Besides top level NMR and computing instrumentation, the laboratory also comprises a biotechnology section with state-of-the-art equipment to work with recombinant proteins and prepare isotopically labelled samples to be used for NMR experiments. more information about the laboratory and about the activities carried on can be found at: http://www.lrm.fi.cnr.it The research projects will focus on the structure determination of paramagnetic metalloproteins, on the study of the processes of protein-protein interaction and to protein folding and on the development of new methods to answer challenging questions. The main systems investigated will be cytochromes, iron-sulfur proteins and copper proteins. The successful applicant should be a highly motivated, creative, energetic, young scientist. While a solid background on NMR of paramagnetic metalloproteins is not necessary, the ability to carry out independently a research project is very important. To apply, please send a curriculum vitae and the names of two academics that can provide reference to: Prof. Bertini Department of Chemistry University of Florence Via Gino Capponi 7 50121 Florence Italy Fax : +39 55 2757555 e-mail : bertini@LRM.FI.CNR.IT From owner-structural-nmr@net.bio.net Wed Feb 04 22:00:00 1998 Path: biosci!biosci!not-for-mail From: Paul Driscoll Newsgroups: bionet.structural-nmr Subject: Postdoctoral Fellowship in Biological NMR Spectroscopy Date: 5 Feb 1998 10:31:17 -0800 Organization: Dept. Biochem. & Mol. Biol., UCL Lines: 73 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <6bcnt7$21n@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net LUDWIG INSTITUTE FOR CANCER RESEARCH University College London School of Medicine Branch (Director: Professor M. D. Waterfield FRS) Postdoctoral Fellowship in Biological NMR Spectroscopy ------------------------------------------------------ Applications are invited for a position, available immediately for up to three years, in Joint UCL/LICR Biological NMR group. The successful candidate will be responsible for pursuing the characterisation of the structural and functional properties of signal transduction proteins, by NMR spectroscopy and other physical techniques. Candidates should have experience of molecular biology and protein expression and purification techniques for the production of recombinant proteins for NMR or X-ray diffraction studies. Candidates would preferably have a degree of familiarity with multi- dimensional NMR spectroscopy and solution structure determination and/or the investigation of the dynamic properties of proteins. The NMR group currently comprises 10 researchers at student to post- doctoral level, is well equipped for molecular biology, protein expression and purification, and NMR spectroscopy (three channel and four channel 600 and 500 MHz Varian spectrometers with pulse shaping and pulse field gradient accessories). We are physically located outside the Ludwig Institute proper in the UCL Biochemistry and Molecular Biology Department. We share a working environment with crystallographers and bioinformatics specialists. We positively encourage NMR group members to attempt crystallisation trials. Additionally we are part of the newly inaugurated Joint Research School (JRS) in Biomolecular Sciences set up in conjunction with the Department of Crystallography at Birkbeck College, headed by Professor Janet Thornton. The JRS is a first-round candidate for a BBSRC National Centre for Structural Biology (decision expected Spring 1998). The salary (currently under review) for this position is in the range UKP 17,641-21,057 plus UKP 2,750 London supplement, dependent on age and experience. [UKP = UK Pounds. Employment would be administered through the Ludwig Institute for Cancer Research, not the University.] Contact Dr. Paul Driscoll (44-171 380 7035) for further details, if required. Applicants should mail or E-mail Dr. P.C. Driscoll Department of Biochemistry and Molecular Biology University College London Gower Street London WC1E 6BT U.K. E-mail: driscoll@biochem.ucl.ac.uk with a curriculum vitae and the names and addresses of three referees, by February 28th 1998. Further details about the LICR and the NMR laboratory can be obtained from the world wide web: http://www.ludwig.ucl.ac.uk/ & http://www.biochem.ucl.ac.uk/ [Apologies to those who receive multiple postings of this announcement] -- Dr. Paul C. Driscoll Royal Society University Research Fellow Group Leader, Joint UCL/LICR NMR Laboratory --------------------------------------------------------------------- Dr. Paul C. Driscoll | Office (answer)phone: (44)-171 380 7035 Dept. Biochem. & Mol. Biol. | Department fax: (44)-171 380 7193 University College London | driscoll@biochem.ucl.ac.uk From owner-structural-nmr@net.bio.net Wed Feb 11 22:00:00 1998 Path: biosci!biosci!not-for-mail From: jbaleja@biba.med.tufts.edu (James D. Baleja) Newsgroups: bionet.structural-nmr Subject: NMR_postdoc Date: 12 Feb 1998 06:22:17 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 37 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <199802091258.HAA28261@biba.med.tufts.edu> NNTP-Posting-Host: net.bio.net Two post-doc positions are available at Tufts Medical School, Boston. The first project is on the investigation of protein-lipid interactions by blood coagulation proteins. The model is system is the C-terminal domain of Factor VIII. [Gilbert, G. E. and Baleja, J. D., Membrane-binding peptide from the C2 domain of Factor VIII forms an amphipathic structure as determined by NMR spectroscopy, Biochemistry 34, 3022-3031 (1995).] [Freedman, S. J., Blostein, M. D., Baleja, J. D., Jacobs, M., Furie, B. C., and Furie, B., Identification of the phospholipid binding site in the vitamin K-dependent blood coagulation protein Factor IX, J. Biol. Chem. 271, 16227-36 (1996).] This position is available starting immediately. The second project is on the structure determination of the proteins from papillomavirus and interacting human proteins. [Lee, K. M., Androphy, E. J., and Baleja, J. D., A Novel Method for Selective Isotope Labeling in Bacterially Expressed Proteins, J. Biomol. NMR 5, 93-96 (1995).] [Veeraraghavan, S., Mello, C. C., Lee, K. M., Androphy, E. J. & Baleja, J. D. (in press, 1998) 1H, 15N, and 13C NMR resonance assignments for the DNA- binding domain of the BPV-1 E2 protein. J. Biomol. NMR] The successful candidate will have experience in NMR techniques and protein purification. Experience in rational drug design and discovery is a big asset. Spectrometers at 300, 500, and 600 MHz field strengths and Silicon Graphics workstations will be available. If interested, please reply to me by E-mail or mail. If C.V.'s are sent by E-mail, they must be in plain text only (not encoded). Sincerely, Jim Baleja E-mail : jbaleja@biba.med.tufts.edu Mail : Dept. of Biochemistry 136 Harrison Ave. Tufts University Boston, MA 02111 From owner-structural-nmr@net.bio.net Fri Feb 27 22:00:00 1998 Path: biosci!biosci!not-for-mail From: "Andre' Pampel" Newsgroups: bionet.structural-nmr Subject: chemical shifts of SDS Date: 28 Feb 1998 12:16:01 -0800 Organization: University of Leipzig Lines: 19 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <34E31A70.41C6@rz.uni-leipzig.de> NNTP-Posting-Host: net.bio.net Hi, does anybody know a paper/book, where the 1H/13C chemical shifts of SDS in micelles were reported? Many thanks in advance for any replies. Cheers Andre' -- ----------------------------------------------------------------- Andre' Pampel University of Leipzig Faculty of Physics and Geosciences Linnestrasse 5 04103 Leipzig Tel/Fax.: ++49-341-9732478/ ++49-341-9732479 email: anpa@rz.uni-leipzig.de http://www.uni-leipzig.de ----------------------------------------------------------------- From owner-structural-nmr@net.bio.net Fri Feb 27 22:00:00 1998 Path: biosci!biosci!not-for-mail From: BIOSCI Administrator Newsgroups: bionet.structural-nmr Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 28 Feb 1998 08:51:23 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 233 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <199802221000.CAA15202@net.bio.net> NNTP-Posting-Host: net.bio.net (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. 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Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! 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If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. From owner-structural-nmr@net.bio.net Fri Feb 27 22:00:00 1998 Path: biosci!biosci!not-for-mail From: Ilya Vakser Newsgroups: bionet.structural-nmr Subject: Postdocs/Graduate Students in Protein Docking and Structure Prediction Date: 28 Feb 1998 08:52:11 -0800 Organization: Medical University of South Carolina Lines: 36 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <34E8933A.2D3A42C7@musc.edu> NNTP-Posting-Host: net.bio.net Applications are invited for postdoctoral and graduate student positions in my laboratory at the Medical University of South Carolina. The positions were advertised in November, however, due to the delayed release of funds, I post them again. The main subjects of the research in the laboratory are computational studies of molecular recognition, docking methodology, structure prediction, and applications to signal transduction pathways and other molecular systems. For more information, see the lab's web site at http://reco3.musc.edu. The following positions are immediately available: Postdoctoral fellow Development of flexible docking techniques for small ligands. Docking methodology for computer-aided drug design. Postdoctoral fellow Modeling of integral membrane receptors. Structure prediction based on the principles of molecular recognition. Graduate student General development of protein docking methodology. Strong programming skills in C are required for all positions. To apply send or email a letter and CV with names of 3 referees. Ilya A. Vakser Assistant Professor of Pharmacology Department of Cell and Molecular Pharmacology Medical University of South Carolina 171 Ashley Avenue Charleston, SC 29425 Email: vakseri@musc.edu, Phone:(803)792-2471, Fax:(803)792-2475