From owner-structural-nmr@net.bio.net Sat Aug 02 23:00:00 1997 Path: biosci!biosci!not-for-mail From: "alexandrescu@ubaclu.unibas.ch"@ubaclu.unibas.ch Newsgroups: bionet.structural-nmr Subject: NMR Postdoctoral Position Basel, Switzerland Date: 3 Aug 1997 11:01:47 -0700 Organization: University of Basel, Switzerland Lines: 44 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <01IM03UXSSN68Y7BY2@ubaclu.unibas.ch> NNTP-Posting-Host: net.bio.net Relay-Version: ANU News - V6.1B10 04/18/95 OpenVMS VAX; site yogi.urz.unibas.ch Path: ubaclu.unibas.ch!nntp Newsgroups: bionet.structural-nmr Subject: NMR Postdoctoral Position Basel, Switzerland Message-ID: <1997Aug3.121630.47579@yogi.urz.unibas.ch> From: Andrei Alexandrescu Date: 3 Aug 97 12:16:30 MET Organization: Biozentrum, U-Basel Nntp-Posting-Host: secsy.bioz.unibas.ch X-Mailer: Mozilla 1.1N (Macintosh; I; PPC) MIME-Version: 1.0 X-URL: news:bionet.structural-nmr Content-Transfer-Encoding: 7bit Content-Type: text/plain; charset=us-ascii Lines: 28 NMR Postdoctoral Position Basel, Switzerland - A postdoctoral position is open immediately for a recent Ph.D. with a background in multidimensional heteronuclear NMR. My group's research interests are: (1) folding of non-homologous proteins that share an oligonucleotide-binding motif, (2) protein dynamics, and to a lesser extent (3) protein structure determination. We have at least 5 proteins/peptide systems that are amenable to 13C/15N labelling. A brand new Bruker AVANCE DRX spectrometer operating at 600 MHz is available for measurements. The instrument is equipped with pulse field gradients, triple resonance probes, and 4 channels for multi-dimensional heteronuclear experiments. Two SGI computers are available for NMR data analysis and structure calculation. Applications including a curriculum vitae and the names of referees familiar with the applicants work should be submitted to: Dr. A. Alexandrescu, Department of Structural Biology, Biozentrum, University of Basel, Klingelbergstr. 70, CH-4056 Basel, Fax: +41-61-267 2109, e-mail: alexandrescu@ubaclu.unibas.ch From owner-structural-nmr@net.bio.net Mon Aug 04 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Mark Girvin Newsgroups: bionet.structural-nmr Subject: NMR "PRINCIPAL ASSOCIATE" POSITION AVAILABLE Date: 5 Aug 1997 01:19:46 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 51 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <3.0.32.19970804222258.00696234@medusa.bioc.aecom.yu.edu> NNTP-Posting-Host: net.bio.net NMR "PRINCIPAL ASSOCIATE" POSITION AVAILABLE NMR Principal Associate position to supervise the Structural NMR Resource at Albert Einstein College of Medicine (AECOM). We're losing our highly-regarded and well-liked staff member to an excellent industrial position in September :( THE POSITION: The position involves a range of duties and skills. Basic instrument supervision and some maintenance are essential parts of the job. The instruments are new, in good shape, and under warrantee for at least the next three years, so this is not too burdensome. Training, assisting, and interacting with users is also a significant part of the position. The implementation and testing of pulse programs is desirable. Collaborative research projects are strongly encouraged, hopefully at least one project and any given time. Research collaborations will help one stay involved with faculty, have results to present at the ENC or equivalent, and maintain one's publishing record. The Principal Associate is a permanent, "hard money" position. Salary increases and promotions are possible in this position, and to be expected. INSTRUMENTATION: The Structural NMR Resource at Albert Einstein College of Medicine (http://www.bioc.aecom.yu.edu/labs/girvlab/nmr) occupies a space specially constructed to house the new Bruker DRX-600 4-channel and DRX-300 2-channel systems, along with substantial computational resources (hardware & software). The new Resource complements the existing 500, 400, and 200 MHz instruments which are used for physiological NMR ENVIRONMENT & LOCATION: AECOM provides an interactive, collaborative, friendly, and stimulating environment. The Biochemistry Department is particularly strong in mechanistic and structural biochemistry (http://www.bioc.aecom.yu.edu/). The Albert Einstein College of Medicine campus is located in a "pleasant residential neighborhood" of the North Bronx: http://leper1.ca.aecom.yu.edu/sggd/pages/overview/neighbor.htm Faculty and staff live in the surrounding neighborhoods, or in Manhattan, or Westchester County, which are both 15 to 45 minute commutes from AECOM, depending on the location. APPLICATIONS: Applications will be reviewed beginning August 18, 1997. The preferred starting date is September to October 1997. Every effort will be made to inform all applicants of the status of the search and their applications (please include an email address). Send Curriculum Vitae and have three letters of reference sent to: Mark Girvin, Biochemistry Department, Albert Einstein College of Medicine, Jack and Pearl Resnick Campus, 1300 Morris Park Ave., Bronx, NY 10461. (girvin@aecom.yu.edu). AECOM is an Equal Opportunity Employer. From owner-structural-nmr@net.bio.net Sat Aug 09 23:00:00 1997 Path: biosci!biosci!not-for-mail From: "R. Andrew Byrd" Newsgroups: bionet.structural-nmr Subject: Position Available Date: 10 Aug 1997 12:17:38 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 44 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <33E8F486.38F8@ncifcrf.gov> NNTP-Posting-Host: net.bio.net NMR Group System Administrator/Computational Support The Macromolecular NMR Section of the ABL-Basic Research Program, NCI-FCRDC has an immediate opening for a motivated individual to handle system administration and scientific computing responsibilities. The Section operates a network of Unix workstations (predominantly SGI with two Sun Sparc workstations as part of NMR spectrometers) and PCs (Pentium and Macintosh). The network includes individual workstations and a computational server. There are also interactions with the Frederick Biomedical Supercomputing Center (FBSC) which operates a range of Cray and multi-processor SGI systems. The successful candidate will have knowledge of Unix, C programming, and system administration plus experience with NMR data processing and/or structure calculations. Experience or familiarity with one or more of the following packages is desired: NMRPipe, ANSIG, XPLOR, Procheck, AQUA, MOLMOL, and Insight. Knowledge of Windows and PC systems is a plus. This individual will interact with a multi- disciplinary group of scientists and collaborate on research projects involving either structure determination or development/enhancement of software tools to accomplish these tasks. Responsibilities will include software and hardware maintenance, upgrades, and planning for future requirements. Persons with recent M.S. or Ph.D degrees involved with NMR and structuredetermination are encouraged to apply; computational experience will substitute for formal computer science training. Minimum qualifications include a B.S. in computer science, chemistry or biochemistry with 3-5 years relevant experience. This is a full-time position with excellent salary and benefits. Interested individuals should contact: R. Andrew Byrd c/o Human Resources/ABL-BRP NCI-FCRDC, P.O. Box B, Bldg. 428 Frederick, MD 21702-1201 email: rabyrd@ncifcrf.gov WWW: http://www-brp.ncifcrf.gov/abl/msl/byrd.html From owner-structural-nmr@net.bio.net Sat Aug 09 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Laura G Barrientos Newsgroups: bionet.structural-nmr Subject: Prolines. Date: 10 Aug 1997 12:15:47 -0700 Organization: Chemistry, Carnegie Mellon, Pittsburgh, PA Lines: 12 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Hello everyone, I am currently assigning a 98aa protein that has 11 prolines. I found difficult to assign the prolines from just COSY, TOCSY, and NOESY. The protein will soon be 15N-labeled. Can anyone suggest me a pulse sequence that would easy the assignment of the prolines? Keep in mind that I will have in hands only the no labeled and the15N-labeled protein. Thanks a lot and have a great weekend, Laura. From owner-structural-nmr@net.bio.net Mon Aug 11 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Istvan Pelczer Newsgroups: bionet.structural-nmr Subject: Re: ultra shims Date: 12 Aug 1997 11:33:01 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 41 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Dear Graham, I suppose you will be working with samples in water, so I certainly advocate the higher number of shims. Cheers, Istvan wwww,wwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwww Istvan Pelczer, Ph.D. Email: ipelczer@princeton.edu Senior NMR Spectroscopist Princeton University Department of Chemistry, Frick Lab., ph# (609) 258 2342 Washington Road fax# (609) 258 6746 Princeton, NJ 08544, USA On 12 Aug 1997, Graham E Jackson wrote: > Dear all > We are looking to purchase a new 600MHz nmr system. There is the > option of going for a 28 shim coil system rather than the standard 20 > coils system. Do the extra shim coils justify the added expense? > Is there anyone who has bought the Ultra shim option and would not do > without it? > Thanks > Graham > > > Graham E Jackson > Associate Professor > Department of Chemistry > University of Cape Town > Cape Town > South Africa > > Fax: (027 21) 6897499 > Tel: (027 21) 6502531 > E-mail: jackson@psipsy.uct.ac.za > > From owner-structural-nmr@net.bio.net Mon Aug 11 23:00:00 1997 Path: biosci!biosci!not-for-mail From: "Graham E Jackson" Newsgroups: bionet.structural-nmr Subject: ultra shims Date: 12 Aug 1997 09:44:46 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 21 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <5sout5$ckq@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net Dear all We are looking to purchase a new 600MHz nmr system. There is the option of going for a 28 shim coil system rather than the standard 20 coils system. Do the extra shim coils justify the added expense? Is there anyone who has bought the Ultra shim option and would not do without it? Thanks Graham Graham E Jackson Associate Professor Department of Chemistry University of Cape Town Cape Town South Africa Fax: (027 21) 6897499 Tel: (027 21) 6502531 E-mail: jackson@psipsy.uct.ac.za From owner-structural-nmr@net.bio.net Wed Aug 13 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Guang Yi Xu Newsgroups: bionet.structural-nmr Subject: NMR Postdoctoral Scientist Position available Date: 14 Aug 1997 13:22:22 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 244 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Genetics Institute, Inc Cambridge, MA Small Molecule Drug Discovery The Small Molecule Drug Discovery group at Genetics Institute is housed in a separate 44,000 sq. ft. facility, located one mile from corporate headquarters. The facility is equipped with the latest technology for modern drug discovery including a 600MHz NMR, X-Ray lab, Computational chemistry, High throughput screening and Medicinal chemistry. The facility houses 50 scientists engaged in the discovery of novel treatments of inflammatory disorders such as Asthma and Rheumatoid arthritis. The interdisplinary team has established itself as a leader in Selectin biology and the role of cytosolic phospholipase A2 in the production of eicosanoids. NMR Postdoctoral Scientist A postdoctoral position is available immediately to join our NMR group. The group has successfully completed the structures of protein up to 20,000 daltons and currently studying protein/ligand interactions. We have an opening for a post doctoral candidate interested in determining the solution structure of proteins, protein dynamics and protein-ligand interactions. The successful candidate will have recently completed a Ph.D and have experience in determining protein structureby NMR. An appreciation of computational and molecular biology is desirable. The NMR facility of SMDD at Genetics Institute, Inc. is equipped with Varian Unity+ 600 with 4 channel capability, multiple R10,000 workstation including an eight processor Challenge. In addition we have state of the art molecular biology and protein biochemistry group to support the structural biology efforts. Please submit CV and cover letter to : Dr. Guang-Yi Xu Small Molecule Drug Discovery Genetics Institute, Inc. 87 Cambridge Park Drive Cambridge, MA 02140. Phone: (617)498-8968, FAX: (617)498-8993, E-mail: gxu@genetics.com begin 644 NMR ad M*%1H:7,@9FEL92!M=7-T(&)E(&-O;G9E"`T+C`I M"CHB3FHP.$PB2T,A(D$X)3-C.64B)"U*(S,B(RTC(2HA)2%$27(Y92(D8F%" M(4XA*2(L(2TB(2HA)R$S(S,A84$*,B$J(2,F+6TA3B$R6"LS(40F0$XA)THA M(BI!2B)$2B%@-'%3(4PD16TA,FUF Newsgroups: bionet.structural-nmr Subject: position available Date: 14 Aug 1997 18:05:05 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 44 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <199708150104.BAA21966@indigo4.bio.uci.edu> NNTP-Posting-Host: net.bio.net NMR Group System Administrator/Computational Support The Macromolecular NMR Section of the ABL-Basic Research Program, NCI-FCRDC has an immediate opening for a motivated individual to handle system administration and scientific computing responsibilities. The Section operates a network of Unix workstations (predominantly SGI with two Sun Sparc workstations as part of NMR spectrometers) and PCs (Pentium and Macintosh). The network includes individual workstations and a computational server. There are also interactions with the Frederick Biomedical Supercomputing Center (FBSC) which operates a range of Cray and multi-processor SGI systems. The successful candidate will have knowledge of Unix, C programming, and system administration plus experience with NMR data processing and/or structure calculations. Experience or familiarity with one or more of the following packages is desired: NMRPipe, ANSIG, XPLOR, Procheck, AQUA, MOLMOL, and Insight. Knowledge of Windows and PC systems is a plus. This individual will interact with a multi- disciplinary group of scientists and collaborate on research projects involving either structure determination or development/enhancement of software tools to accomplish these tasks. Responsibilities will include software and hardware maintenance, upgrades, and planning for future requirements. Persons with recent M.S. or Ph.D degrees involved with NMR and structuredetermination are encouraged to apply; computational experience will substitute for formal computer science training. Minimum qualifications include a B.S. in computer science, chemistry or biochemistry with 3-5 years relevant experience. This is a full-time position with excellent salary and benefits. Interested individuals should contact: R. Andrew Byrd c/o Human Resources/ABL-BRP NCI-FCRDC, P.O. Box B, Bldg. 428 Frederick, MD 21702-1201 email: rabyrd@ncifcrf.gov WWW: http://www-brp.ncifcrf.gov/abl/msl/byrd.html From owner-structural-nmr@net.bio.net Tue Aug 19 23:00:00 1997 Path: biosci!biosci!not-for-mail From: "[31mThe Brewer [37m" Newsgroups: bionet.structural-nmr Subject: Average Structure from an ensemble. Date: 19 Aug 1997 21:27:02 -0700 Organization: University of Virginia Lines: 13 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Hello, Can any one out there tell me how to generate an average structure from an ensemble. We have insightII and I would prefer that, but I'll be glad to hear about other methods too. Thanks -- Jaison Jacob Chemistry Department Univ. of Virginia From owner-structural-nmr@net.bio.net Tue Aug 19 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Mark Girvin Newsgroups: bionet.structural-nmr Subject: NMR "PRINCIPAL ASSOCIATE" POSITION (UPDATED) Date: 19 Aug 1997 21:26:32 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 57 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <3.0.32.19970819113512.008f7220@medusa.bioc.aecom.yu.edu> NNTP-Posting-Host: net.bio.net NMR "PRINCIPAL ASSOCIATE" POSITION AVAILABLE - UPDATED NMR Principal Associate position to supervise the Structural NMR Resource at Albert Einstein College of Medicine (AECOM). THE POSITION: Applicants for this position should hold a Ph.D. degree, preferably in Chemistry or Biochemistry. Experience in multidimensional NMR is essential. UNIX software and NMR hardware experience is desirable. This position involves a range of duties. Basic instrument supervision and some maintenance are essential parts of the job. The instruments are new, in good shape, and under warrantee for at least the next three years, so this is not too burdensome. Training, assisting, and interacting with users is also a significant part of the position. The implementation and testing of pulse programs is desirable. Collaborative research projects are strongly encouraged, hopefully at least one project and any given time. Research collaborations will help one stay involved with faculty, have results to present at the ENC or equivalent, and maintain one's publishing record. The Principal Associate is a permanent, "hard money" position. Salary increases and promotions are possible in this position, and to be expected. INSTRUMENTATION: The Structural NMR Resource at Albert Einstein College of Medicine (http://www.bioc.aecom.yu.edu/labs/girvlab/nmr) occupies a space specially constructed to house the new Bruker DRX-600 4-channel and DRX-300 2-channel systems, along with substantial computational resources (hardware & software). The new Resource complements the existing 500, 400, and 200 MHz instruments which are used for physiological NMR ENVIRONMENT & LOCATION: AECOM provides an interactive, collaborative, friendly, and stimulating environment. The Biochemistry Department is particularly strong in mechanistic and structural biochemistry (http://www.bioc.aecom.yu.edu/). The Albert Einstein College of Medicine campus is located in a "pleasant residential neighborhood" of the North Bronx: http://leper1.ca.aecom.yu.edu/sggd/pages/overview/neighbor.htm Faculty and staff live in the surrounding neighborhoods, or in Manhattan, or Westchester County, which are both 15 to 45 minute commutes from AECOM, depending on the location. APPLICATIONS: I had originally hoped to begin reviewing applications on August 18. With everyone's end of the summer schedule of meetings and vacations, this turned out to be impossible. So, review of applications will begin September 1, and continue until the position is filled. Since we're losing our highly-regarded and well-liked staff member to an excellent industrial position in September, the preferred starting date is October 1997 - i.e. as soon as possible. Every effort will be made to inform all applicants of the status of the search and their applications (please include an email address). Send Curriculum Vitae and have three letters of reference sent to: Mark Girvin, Biochemistry Department, Albert Einstein College of Medicine, Jack and Pearl Resnick Campus, 1300 Morris Park Ave., Bronx, NY 10461. (girvin@aecom.yu.edu). AECOM is an Equal Opportunity Employer. From owner-structural-nmr@net.bio.net Tue Aug 19 23:00:00 1997 Path: biosci!biosci!not-for-mail From: fmohdsom.chem.se.dundee@its.dundee.ac.uk Newsgroups: bionet.structural-nmr Subject: images to PC Date: 20 Aug 1997 10:37:01 -0700 Organization: University of Dundee Lines: 18 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net I have been looking on the net regarding MR image processing on the PC. Over here I am using Bruker X32 to process the image. However, more and more publications are asking for the softcopy of everything including images. We used to just send the copy produced from the video copy processor or take a photograph of the image on the screen and send the hard copy of it. Now, we have to scan the photograph so that it can be included directly into the paper. Is there anway I can get the image directly from Bruker X32 to PC and have it converted to PC format without going through the photographic session? Our X32 is not networked to the PC but we are getting Bruker Paravision (still waiting like endlessly) running on SG in 1 month (I guess) which will be networked to the PC. Thank you. Fauzi From owner-structural-nmr@net.bio.net Tue Aug 19 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Steve Pascal Newsgroups: bionet.structural-nmr Subject: postdoctoral position Date: 20 Aug 1997 14:00:39 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 35 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <9708201949.AA18840@oxbow.biophysics.rochester.edu> NNTP-Posting-Host: net.bio.net A postdoctoral position will be available in my laboratory beginning this fall/winter, to study the structure and dynamics of protein complexes involved in transcriptional regulation. Within the last two years, the Department of Biochemistry and Biophysics at the University of Rochester has hired two NMR spectroscopists, an X-ray crystallographer and installed a fully equipped Varian Unity+ 600 MHz spectrometer as part of a structural biology initiative. Applicants with experience in multi-nuclear NMR spectroscopy and/or protein expression/purification should send a CV along with telephone numbers and email addresses of three people familiar with their work to the address below. Email responses are encouraged. Thank You =========================================== Steve Pascal Assistant Professor Box 712 Department of Biochemistry & Biophysics University of Rochester Medical Center 601 Elmwood Ave Rochester, NY 14642 716-273-4832 (voice) 716-275-6007 (fax) =========================================== From owner-structural-nmr@net.bio.net Tue Aug 19 23:00:00 1997 Path: biosci!biosci!not-for-mail From: =?iso-8859-1?Q?H=E5rd_Karl?= Newsgroups: bionet.structural-nmr Subject: Protein NMR Spectroscopist Date: 19 Aug 1997 21:30:15 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 36 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Protein NMR Spectroscopist The Astra Structural Chemistry Laboratory (ASCL) is a new corporate competence center to provide high quality structural information on drug targets for preclinical projects in the different Astra product companies. The laboratory is currently being established at the Astra H=E4ssle site in G=F6teborg, Sweden, in a new 5000 m2 building. It is composed of 3 main disciplines: macromolecular crystallography (2 complete X-ray systems), macromolecular NMR (800 and 600 MHz), and protein engineering. The initial number of people in the laboratory will be 20. We are now looking for a motivated PhD-level NMR spectroscopist to join the macromolecular NMR group. Experience with structure determination of isotopically labelled proteins is necessary. The NMR group will work in close collaboration with the X-ray crystallography and the protein engineering groups at the ASCL. For more information, please contact Karl Hard, Head of Protein NMR, tel. +46 31 776 1604, karl.hard@hassle.se.astra.com, or Jan Hoflack, Director ASCL, +46 31 776 2715, jan.hoflack@hassle.se.astra.com, or Bob Carter, Project Manager ASCL, +46 31 776 1621, bob.carter@hassle.se.astra.com The complete advertisement, including ten additional vacancies at the ASCL, has been published in the July 10 issue of Nature and in the July 11 issue of Science. For further information about Astra: http://www.astra.com Applications (in English) with full details should be marked "Macromolecular NMR 76/97", and sent to the following address before August 31, 1997: Astra H=E4ssle AB, Human Resources, Att. Linda Wikstrom, S-431 83 Molndal, Sweden. Fax no. +46 31 776 3746.=20 From owner-structural-nmr@net.bio.net Wed Aug 27 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Ian Armitage Newsgroups: bionet.structural-nmr Subject: Re: NMR Spectroscopist position Date: 28 Aug 1997 10:29:24 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 45 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Attached below is an ad that is scheduled to appear in the 8/25 issue of the C&EN. David Live, the Manager of the NMR facility here at the U of Minn, and I would be very grateful if you would bring this opening to the attention of any qualified candidates. Thanks, Ian M. Armitage Department of Biochemistry University of Minnesota 5-130 BSBE 312 Church Street S.E. Minneapolis, MN 55455 Tel:office 612-624-5977; Lab 612-626-4227 Fax: 612-625-2163 Email: ian@dimer.biochem.umn.edu Web site: http://bturn.biochem.umn.edu/ ***************************************************************** AD FOR CHEMICAL AND ENGINEERING NEWS FOR 8/25/97 PUBLICATION SECTION: EMPLOYMENT-ACADEMIC POSITIONS NMR Spectroscopist > > > > Research Associate/NMR Spectroscopist: University of Minnesota > > Structural Biology NMR Facility is seeking an individual to > > participate in instrument maintenance, user training, and NMR data > > collection and collaboration. Facilities > > include: 500, 2-600 & 800 MHz INOVA NMRs. A Ph.D. and experience in > > NMR spectroscopy of biopolymers are required. Applicants with > > experience using Varian systems, UNIX and > > current multiple dimensional NMR experiments will be preferred. > > Postdoc experience is desirable. Salary range is $25,000- $40,000. > > Interested persons should send letter of application, resume, and 3 > > reference letters to Chair, Search Committee, Dept. of > > Biochemistry-Med. School, 4-225 Mlrd Hall, 435 Delaware St. SE, > > Mpls., MN 55455 by 9/7/97. The University of Minnesota is an equal > > opportunity educator and employer.. From owner-structural-nmr@net.bio.net Wed Aug 27 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Laurie Martensen Newsgroups: bionet.structural-nmr Subject: Workshop series Date: 28 Aug 1997 10:30:14 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 36 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <3.0.16.19970822112347.5cbfbcbc@146.202.6.217> NNTP-Posting-Host: net.bio.net Molecular Simulations, Inc. and Silicon Graphics present FELIX 97.0 Workshop Series Felix 97.0 THE NEW GENERATION OF NMR SOFTWARE New and Improved - Easy to use - More streamlined This workshop series will introduce you to the new features in FELIX 97.0, and give you hands-on experience for analyzing your own data. To register for one of the workshops, visit the special promotions area of our Website (www.msi.com) or send an email to felix97@msi.com September 15, San Diego, CA September 17, Mountain View, CA September 19, Schaumburg, Il September 22, Research Triangle Park, NC September 24, Philadelphia, PA September 26, Boston, MA October 6, Cambridge, UK October 8, Munich, Germany October 10, Paris, France Laurie Martensen Project Manager, Direct Marketing Molecular Simulations Inc. 9685 Scranton Road, San Diego, CA 92121-3752 (619) 546-5554, Fax: (619) 597-9780 E-mail: lxm@msi.com, Web: http://www.msi.com From owner-structural-nmr@net.bio.net Wed Aug 27 23:00:00 1997 Path: biosci!biosci!not-for-mail From: leblanc@dingo.NIEHS.NIH.GOV (Darryl Leblanc) Newsgroups: bionet.structural-nmr Subject: waveform gen for shaped pulses Date: 28 Aug 1997 12:26:41 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 33 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <199708121930.PAA08113@dingo.niehs.nih.gov> NNTP-Posting-Host: net.bio.net Hello all, Is there a concensus on the number of waveform generators needed to perform the latest triple resonance experiments for protein structure determination (the sequences in protein pack, for example)? My impression is that in most cases shaped pulses are needed most on the channels used for 1H and 13C, so two waveform generators should be sufficient. Are there any advocates out there for having 3 or even 4 wfg? Also, are shaped gradients being used by many people? Thanks for your time and opinions. Darryl PS I am referring to Varian instrumentation, as I don't know what Bruker calls their hardware for generating shaped pulses. _____________________________________________ _____________________________________________ Darryl A. LeBlanc, Ph.D leblanc@niehs.nih.gov Phone (919) 541-0733 http://www.niehs.nih.gov/dirnmr/ National Institute of Environmental Health Sciences Mail Drop MR-03 Laboratory of Structural Biology Research Triangle Park, NC 27709 _____________________________________________ _____________________________________________ From owner-structural-nmr@net.bio.net Wed Aug 27 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Werner Braun Newsgroups: bionet.structural-nmr Subject: Postdoc position at UTMB, Galveston, TX, USA Date: 28 Aug 1997 10:29:49 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 18 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <199708222212.RAA22531@tocsy.utmb.edu> NNTP-Posting-Host: net.bio.net A postdoc position is available in the Computational Biology Group of the Sealy Center for Structural Biology, UTMB Galveston TX, to model 3D structures of important protein drug targets. Candidates should have extensive experience in programming (Fortran, C++, GUI interfaces) and some aspects of molecular biology and/or Nuclear Magnetic Resonance techniques. Computational facilities include a high-performance supercomputer Cray J90 and several SGI graphics workstations. Some information on the research activities can be obtained on the WEB page http://www.scsb.utmb.edu/comp_biol.html/ Interested scientists should contact for further details: Dr. Werner Braun, Sealy Center for Structural Biology, Phone: (409) 747-6810 FAX: (409) 747-6850 E-mail: werner@nmr.utmb.edu From owner-structural-nmr@net.bio.net Thu Aug 28 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Francois Dupradeau Newsgroups: bionet.structural-nmr Subject: Modify a force field Date: 29 Aug 1997 13:46:43 -0700 Organization: Laboratoire de Biophysique Lines: 11 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <3406CD3E.446B@sa.u-picardie.fr> NNTP-Posting-Host: net.bio.net Hi, I look for informations for modifying the cvff force field (for peptides). I am interested to introduce parameters for the sulfonate group (RSO3-). Does anyone know references for this work (or similar work of similar group)? Thank you From owner-structural-nmr@net.bio.net Thu Aug 28 23:00:00 1997 Path: biosci!biosci!not-for-mail From: thomas Newsgroups: bionet.structural-nmr Subject: heteronuclear 3J(C-H)-coupling constants Date: 29 Aug 1997 13:47:54 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 20 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <5u5tmq$dna@mserv1.dl.ac.uk> NNTP-Posting-Host: net.bio.net Dear netters !! I want to measure the 3J(C-H) coupling constants for my disaccharide and I found a lot of possibilities in the literature. Does anybody know a good method ?? I try the optimazation with the HMBC experiment, but I don't understand excactly the fitting procedure. Can anybody help ?? Thanks in advance Thomas ************************************************************************ Thomas Haselhorst e-mail : thomas@johann.chemie.mu-luebeck.de Institute of Chemistry Medical University of Luebeck Tel. x49 451 500 4239 Ratzeburger Allee 160 Fax. x49 451 500 4241 23538 Luebeck, Germany ************************************************************************ From owner-structural-nmr@net.bio.net Sun Aug 31 23:00:00 1997 Path: biosci!biosci!not-for-mail From: Xiaolian Gao Newsgroups: bionet.structural-nmr Subject: NMR/Computation postdoctoral position Date: 1 Sep 1997 10:15:18 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 26 Sender: daemon@net.bio.net Approved: raman@hemebase.bio.uci.edu Distribution: world Message-ID: <3.0.32.19970901121102.006f26fc@kitten.chem.uh.edu> NNTP-Posting-Host: net.bio.net Applications are invited for an NMR/Computation postdoctoral position in the Chemistry Department at the University of Houston. Experiences in high resolution structural NMR and/or molecular modeling areas are highly desirable. Houston has seen a rapid growth in development of biotechnology. Our NMR Laboratory is a member of the Institute for Molecular Design and the joint biophysical training programs involving several Universities in the area. Strong candidates may also be considered for the NIH postdoctoral fellowship (citizenship or permanent residence is required). The position offers an excellent opportunity for scientific excitement and career advancement. Salary is highly competitive and commensurate with experience. Please send resume and three letters of reference to Dr. Xiaolian Gao, Department of Chemistry, University of Houston, Houston, TX 77204-5641. Email: gao@kitten.chem.uh.edu Web sites: http://www.chem.uh.edu/www/gao/intro.html http://www.bioc.rice.edu http://condor.bcm.tmc.edu/SCBMB/scbmb.html Xiaolian (pronounce as Shao-lin) Gao Dept. Chemistry University of Houston Houston, TX 77204-5641 Tel: 713 743-2805, 2806 Fax: 713 743-2709 gao@kitten.chem.uh.edu or xgao@uh.edu