Hi, there. lipofectamine is toxic for mice. This is serious problem.Apoptosis
and necrosis are double edge on cancer research for chemotherapy.
Please study more Tumor-Necrosis Factor.
So that you can find the best solution to choosing chemical drugs for in
vivo mice study. You might be careful about lethal dosage.
It is not appropriate way to use in vitro study result for vivo study.
Take care.
masako