The mail prefs dialog asks for your return e-mail address, and your preferred SMTP mail host. These addresses may be similar.
Return e-mail address: This is where another person should send mail so it will reach you.
Example: Bob.Jones@Bio.Indiana.Edu
or: bjones@sunflower.bio.indiana.edu
SMTP Mail host: This is the internet address of the computer thru which SeqPup will send out mail to the rest of the world.
Example: Sunflower.Bio.Indiana.Edu