README.TXT  BRIEF EXPLANATIONS OF FILES ON
                          DISK SNEATH_ST1

                There are the following files:

        README.TXT      This file.

        phs5t14.bas     Program (GWBASIC or QBASIC) to screen a
                        matrix of molecular sequences for atypical
                        sequence comparisons using a modified
                        Sherman statistic.  
                                        The program can be used
                        on either nucleotide or protein sequences,
                        and compares all the t(t-1)/2 comparisons
                        for t sequences.  It prints the Sherman
                        statistic w and also functions of it,
                        including the normal standard error score z,
                        the corresponding normal probability P, 
                        and for convenience, -2 ln P which is useful
                        for some statistical purposes.
                                        The program also gives several
                        summaries of the results for individual
                        sequences and the distances between sequences.

        phs5t14c.bas    A version of phs5t14.bas which corrects for
                        the constant-site effect for the three codon
                        positions.  

        phs6t06.bas     Program (GWBASIC or QBASIC) to simulate the
                        addition of constant sites to randomly-placed
                        differences in a molecular sequence comparison.
                        This sequence consists of similarities, S, and 
                        differences, D, and uses the modified Sherman
                        statistic.  The output gives the values of
                        w and some derivatives for various values of
                        the number off added constant sites, c.

        5t14a.dat       A file of test data with a recombinant sequence,
                        so as to obtain a high probability for one
                        comparison, and including numbers of constant
                        sites as a final row.  To be copied
                        to file phs5t14.dat which is the input file
                        for programs phs5t14.bas and phs5t14c.bas.
                                NOTE THAT THIS WILL OVERWRITE THE
                        PREVIOUS phs5t14.dat;  therefore do not rename
                        any files, but copy them;  the originals will
                        then be unchanged.

        5t14b.dat       A small test file to copy to phs5t14.dat.

        5t14c.dat       Another small test file to be copied to 
                        phs5t14.dat.

        pimelmt.dat     A nucleotide matrix of mitochondria of
                        Pimelia beetles, for full testing of programs
                        phs5t14.bas and phs5t14c.bas after it has been
                        copied to phs5t14.dat.

   Cheers,  Michael.

Michael J. Sackin, Senior Computer Officer, Dept of Microbiology &
Immunology, University of Leicester, PO Box 138, University Road,
Leicester  LE1 9HN, UK                 email: mjs@le.ac.uk
Phone: (+44) 116-252 2957    FAX: (+44) 116-252 5030