The programs in lintre.unix.tar.Z are  for (1) testing the molecular clock on 
a given topology of a phylogenetic tree and (2) making linearized trees 
(reestimating branch lengths under the assumption of constant rate of 
evolutions. The data that can be used are nucleotide or amino acid sequences.

For details of the methods, please look at "Phylogenetic tests of the 
molecular clock and linearized trees" (Molecular Biology and Evolution 12:
823-833, 1995).

(1) Ftp lintre.unix.tar.Z and lintre.unix.readme onto your system in the binary mode.
(2) Type "uncompress lintre.unix.tar.Z".
(3) Type "tar xvf lintre.unix.tar".
(4) Read the read.me file first.


If you have problems or comments, please send email to:

       takezaki@tuebingen.mpg.de


  April 4, 2001



                                  Naoko Takezaki
                                  Max-Planck Institute fuer Biologie
                                  TEL +49-7071-601-276
                                  FAX +49-7071-600=473
                                  Email : takezaki@tuebingen.mpg.de