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Article: 7 of bionet.molbio.gdb
Newsgroups: bionet.molbio.gdb
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From: ken@welchgate.welch.jhu.edu (Ken Fasman)
Subject: GDB Fact Sheet
Message-ID: <1992Jun12.224451.25920@welchgate.welch.jhu.edu>
Organization: Johns Hopkins Univ. Welch Medical Library
Date: Fri, 12 Jun 1992 22:44:51 GMT
Lines: 89

                          GDB(TM) and OMIM(TM)
                          ====================

               Gene Mapping Data and Phenotypic Descriptions
          in support of the International Human Genome Initiative

                  an international collaboration hosted at
           The Johns Hopkins University School of Medicine and
                     the William H. Welch Medical Library
                          Baltimore, Maryland USA 

GDB (Genome Data Base)
----------------------
GDB contains human gene mapping information and has been available since
1990. Members of the Human Gene Mapping Workshops (HGMW) are responsible
for entering and continuously updating the data. Users can retrieve the
following types of information:

	o loci  (genes, fragile sites, DNA segments) arranged by map location;
		data include symbol, name, chromosome location, MIM number
	o polymorphisms and alleles
	o probes  (cloned probes, PCR primers, ASOs)
	o sources  (journals, books, theses, personal communications)
	o contacts  (for probes and GDB/OMIM users)
	o maps  (genetic and physical maps).

There is a direct searching link through MIM numbers to the corresponding
entries in OMIM.

OMIM (Online Mendelian Inheritance in Man)
------------------------------------------
OMIM, the full-text database of Dr. Victor A. McKusick's Mendelian Inher-
itance in Man (MIM), has been available since 1987 and is updated daily.
Entries are arranged by clinical disorder or trait and include the
following types of information:

	o name
	o MIM number
	o clinical observations	
	o inheritance patterns	
	o references	
	o allelic variants  (present in many entries)
	o chromosome location  (present in many entries)
	o defective gene products  (associated with many entries)
	o linkage information
	o date last edited.

Searchers can locate information in OMIM and then use the MIM number or
chromosome location to find additional information in GDB. A direct
searching link through MIM numbers to GDB is planned for the future.

Online Access to GDB and OMIM
-----------------------------
GDB and OMIM are available via SprintNet(R)(formally Telenet(R)) or Internet.

   SprintNet access requirements:
	IBM-compatible PC, Apple Macintosh, or terminal
	   (VT100 is adequate; VT220 supports function keys)
	communications software 
	   (a commercially available communications program or WelComm
	   for PC / WelComm for Macintosh:  prepared specifically for
	   accessing GDB/OMIM)
	modem  (Hayes-compatible if using WelComm software)

   Internet access requirements:
	communications software
	   (such as public-domain package NCSA Telnet for PC and Macintosh)

Available Services
------------------
The following services are currently available at no cost.
	o account set-up
	o WelComm software
	o documentation
	o training
	o online searching
	o help-line support

For additional information and registration, please contact:

	GDB User Support
	William H. Welch Medical Library
	1830 E. Monument Street, Third Floor
	Baltimore, MD 21205 USA
	Phone:	(410) 955-7058
	Fax:	(410) 955-0054 or (410) 614-0434
	Internet: help@welch.jhu.edu

March 1992