The programs in lintrdos.exe are  for (1) testing the molecular clock on 
a given topology of a phylogenetic tree and (2) making linearized trees 
(reestimating branch lengths under the assumption of constant rate of 
evolutions. The data that can be used are nucleotide or amino acid sequences.

For details of the methods, please look at "Phylogenetic tests of the 
molecular clock and linearized trees" (Molecular Biology and Evolution 12:
823-833, 1995).

(1) Ftp lintrdos.exe and lintrdos.readme onto your system in the binary mode.
(2) Type lintrdos
(3) Read the read.me file first.

The programs are compiled for MSDOS.
There are 32 bit executables and 16 bit executables. 16 bit executables
may work only a small data set.
The source codes of the programs are availble in files: njboot.src.exe,
tpcv.src.exe, branch.src.exe, branbst.src.exe, postree.src.exe.

If you have problems or comments, please send email to:


          takezaki@koryuw01.soken.ac.jp


                                  Naoko Takezaki
                                  The Graduate University for Advanced Studies
                                  Hayama, Kanagawa 240-0193
                                  TEL +468-58-1580
                                  FAX +468-58-1544
                                  Email : takezaki@koryuw01.soken.ac.jp